epic road trip routes

Are you ready for a Road Trip? Explore these eleven incredible cross-country road trip routes across the U.S.!

Pacific Coast

Border to Border

The Road to Nowhere

The Great River Road

Appalachian Trail

Atlantic Coast

The Great Northern

The Oregon Trail

The Loneliest Road

Southern Pacific

Classic American Road Trips

Pacific Coast Highway

Starting at the northwest tip of the United States at Washington’s Olympic National Park and remaining within sight of the ocean all the way south to sunny San Diego, this 1,650-mile, mostly two-lane road trip takes in everything from temperate rainforest to near-desert.

Highlights along the Pacific Coast Route: Olympic National Park (WA), Three Capes Loop (OR), Redwood National Park (CA)

Historic Route 66

The romance of traveling along historic Route 66 from where it starts in Chicago and ends in Los Angeles continues to captivate people around the world. If you’re looking for great displays of neon signs, rusty middle-of-nowhere truck stops, or kitschy Americana, do as the song says and “get your kicks on Route 66.”

Highlights along Route 66: Chicago (IL), Meramec Caverns (MO), Tucumcari (NM), Painted Desert (AZ), Santa Monica (CA)

• Barnes & Noble
• Books-A-Million
• Indigo (Canada)
• Powell's Books
• Apple Books

Running coast-to-coast from San Francisco to Ocean City, Maryland, “The Loneliest Road in America” is a 3,200-mile odyssey from sea to shining sea. US-50 passes through a dozen different states, four state capitals, and the nation’s capital, Washington, D.C.

Highlights along the Loneliest Road: South Lake Tahoe (CA), Moab (UT), The Million Dollar Highway (CO), Washington D.C.

Following in the footsteps of pilgrims and pioneers, US‑20 takes in a little of everything during its two-lane trek from Oregon’s rugged coast to the glorious sea and sand of Cape Cod.

Highlights along the Oregon Trail: Cannon Beach (OR), Fort Boise (ID), Yellowstone National Park (WY), Mt Rushmore & Carhenge (NE)

Dubbed the Great Northern in memory of the pioneer railroad that parallels the western half of the route, US‑2 is truly the most stunning and unforgettable, not to mention longest, of all the great transcontinental road trips.

Highlights along the Great Northern: Tumwater Canyon (WA), Glacier National Park (MT), Lake Michigan (MI), Acadia National Park (ME)

The Appalachian Trail

This driving route of the Appalachian Trail parallels the epic hike. From the top of New England to the heart of Dixie, it takes you through continuous natural beauty—without the sweat, bugs, or blisters.

Highlights along the Appalachian Trail: Mt. Washington (NH), The Poconos (PA), Shenandoah National Park (VA), Great Smoky Mountains National Park (NC)

Old Man River, Father of Waters, “body of a nation,” Big Muddy: By any name, the mighty Mississippi River cuts a mythic figure across the American landscape. Tag along from its headwaters in Minnesota to where it meets the sea in Louisiana via the GRR.

Highlights along the Great River Road: Main Street USA (WI), St. Louis (MO), Natchez Trace Parkway (MS), New Orleans (LA)

Starting at the Statue of Liberty and ending with a drive across the Overseas Highway to free-wheeling Key West, these almost 2,000 miles of roadway run within earshot—if not sight—of the Atlantic Ocean.

Highlights along the Atlantic Coast: The Statue of Liberty (NJ), Assateague Island National Seashore (MD), Savannah (GA), Cocoa Beach (FL)

Starting at Canada’s Jasper National Park, and winding down in the Sonora Desert, this route traverses some of the wildest and most rugged lands imaginable: mighty mountains, glaciated valleys, raging rivers, and two very different deserts.

Highlights along the Border to Border Route: Columbia Icefield (AB), Bitterroot Mountains (MT), The Extraterrestrial Highway (NV), Joshua Forest Parkway (AZ)

Once the only entirely paved route from Canada to “Old Mexico,” US‑83 cuts across America’s heartland and remains a must-do long-distance byway—transnavigating this broad, odd nation without once grazing a conventional tourist destination.

Highlights along the Road to Nowhere: Sitting Bull Memorial (SD), Nebraska Sand Hills (NE), Monument Rocks (KS), Paint Rock Pictographs (TX)

Following old US-80 and its contemporary equivalents takes you through more varied cultural and physical landscapes than you’ll find along any other cross-country route. From deserts to bayou swamps and Tex-Mex to barbecue, this route offers a full-flavored taste of America.

Highlights along Southern Pacific: The Desert View Tower (CA), Tombstone (AZ), Roswell (NM), Civil Rights Movement National Historic Trail (AL)